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& Canada chronic pain management frameworks boosting accessibility Indias CSIR enabling domestic paracetamol manufacturing for self-reliance Recent Breakthroughs & Announcements Vertexs suzetrigine (Journavx) wins FDA approval for acute pain MANKIND PHARMA LTD enters topical pain relief space with Nimulid Strong, targeting neck pain Kyoto University unveils new analgesic "ADRIANA" with selective 2B-adrenoceptor blocking Xgene Pharmaceutical reports positive Phase 2b results for XG005 oral pain tablets Why It Matters As 530M+ people globally live with osteoarthritis and 30-40% self-medicate using OTC drugs, the world is demanding safer, faster, accessible pain relief solutions

Mitochondrial membrane potential (m) has been considered a good indicator of cells health 30 , as it is critical for maintaining the physiological function of the respiratory chain to generate ATP in mitochondria